Sa ido kan abun ciki na glucose akan layi don ciyarwa na ainihin lokacin don tabbatar da ingantaccen aikin haifuwa.
Injiniyan biofermentation yana ɗaya daga cikin mahimman abubuwan injiniyan biopharmaceutical na zamani, samun samfuran sinadarai da ake buƙata ta hanyar haɓakar ƙwayoyin cuta.Tsarin ci gaban ƙananan ƙwayoyin cuta ya haɗa da matakai huɗu: lokacin daidaitawa, lokacin log, lokacin tsayawa, da lokacin mutuwa.A lokacin lokacin tsayawa, babban adadin samfuran rayuwa suna tarawa.Wannan kuma shine lokacin da ake girbe samfuran a yawancin halayen.Da zarar wannan lokaci ya wuce kuma lokacin mutuwa ya shiga, duka ayyukan ƙananan ƙwayoyin cuta da kuma tsabtar samfurori za su yi tasiri sosai.Saboda da rikitarwa na nazarin halittu halayen, da repeatability na fermentation tsari ba shi da kyau, kuma ingancin iko yana da kalubale.Yayin da tsarin ke tasowa daga dakin gwaje-gwaje zuwa ma'aunin matukin jirgi, kuma daga sikelin matukin jirgi zuwa babban samarwa, rashin daidaituwa na iya faruwa cikin sauki.Tabbatar da cewa ana kiyaye halayen fermentation a cikin tsayayyen lokaci na tsawon lokaci shine batun da ya fi dacewa yayin haɓaka aikin injiniyan fermentation.
Don tabbatar da cewa ƙwayar ƙwayar cuta ta ci gaba da kasancewa cikin ƙarfi da kwanciyar hankali lokacin girma yayin haifuwa, yana da mahimmanci don kiyaye abun ciki na abubuwan da ake buƙata na makamashi kamar glucose.Yin amfani da spectroscopy na kan layi don saka idanu akan abun ciki na glucose a cikin broth na haifuwa a cikin ainihin lokaci shine tsarin fasaha mai dacewa don sarrafa tsarin biofermentation: ɗaukar canje-canje a cikin tattarawar glucose azaman ma'auni don kari da ƙayyade yanayin ƙwayar ƙwayar cuta.Lokacin da abun ciki ya faɗi ƙasa da aka saita, ana iya aiwatar da kari da sauri bisa sakamakon sa ido, yana haɓaka inganci da ingancin biofermentation sosai.Kamar yadda aka nuna a cikin zanen da ke ƙasa, ana zana reshe na gefe daga ƙaramin tanki na fermentation.Binciken spectroscopy yana samun siginar ruwa na fermentation na ainihin-lokaci ta wurin tafki, yana ba da damar gano adadin glucose a cikin ruwan hadi har ƙasa da 3‰.
A gefe guda, idan ana amfani da samfurin kan layi na broth fermentation da gwajin dakin gwaje-gwaje don sarrafa tsari, sakamakon gano jinkiri na iya rasa mafi kyawun lokacin kari.Bugu da ƙari, tsarin yin samfur na iya shafar tsarin fermentation, kamar gurbatawa daga ƙwayoyin cuta na waje.
Lokacin aikawa: Dec-07-2023